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This specialized region of your sarcolemma permits the near apposition with the L-type Ca2+ channel towards the Ca2+ launch channels in the sarcoplasmic reticulum. The sarcoplasmic reticulum serves the two to be a resource and an internal retail store of cytosolic Ca2+ expected for excitation-contraction coupling. The contractile apparatus is usual

Myocyte hypertrophy and interstitial fibrosis are frequent conclusions in cardiac allografts and therefore are not automatically associated with the cause of allograft failure [241,242]. Myocyte hypertrophy is likely a compensatory response to reparative or reactive fibrosis and/or systemic hypertension. It is very prevalent in allografts more than

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